Lymphatic and Immune System Diseases: Interactive Learning Quizzes

Question 1

Which type of lymphoid tissue is located within the digestive tract?

Accepted Answer

Peyer's patches

Answer

Tonsils

Answer

Thymus

Answer

Spleen

Question 2

Hodgkin lymphoma is characterized by the presence of which abnormal cell type?

Accepted Answer

Reed-Sternberg cells

Answer

Plasma cells

Answer

Lymphoblasts

Answer

Neutrophils

Question 3

The thymus gland is primarily responsible for:

Accepted Answer

T cell maturation

Answer

B cell production

Answer

Antibody synthesis

Answer

Hormone secretion

Question 4

Which type of hypersensitivity reaction involves the activation of IgE antibodies?

Accepted Answer

Type I

Answer

Type II

Answer

Type III

Answer

Type IV

Question 5

Where is Immunoglobulin A (IgA) predominantly found?

Accepted Answer

Saliva

Answer

Serum

Answer

Cerebrospinal fluid

Answer

Lymph nodes

Question 6

In non-Hodgkin lymphoma, which type of immune cell is primarily affected?

Accepted Answer

B cells

Answer

T cells

Answer

Macrophages

Answer

Neutrophils

Question 7

What is the primary treatment modality for childhood acute lymphoblastic leukemia?

Accepted Answer

Chemotherapy

Answer

Radiation therapy

Answer

Stem cell transplant

Answer

Surgery

Question 8

What is the primary function of the lymphatic system?

Accepted Answer

Immune defense

Answer

Fluid balance

Answer

Hormone production

Answer

Blood purification

Question 9

Which of the following is NOT a type of primary immunodeficiency disorder?

Accepted Answer

Human immunodeficiency virus infection

Answer

Severe combined immunodeficiency

Answer

X-linked agammaglobulinemia

Answer

DiGeorge syndrome

Question 10

What is the distinctive morphological feature of Langerhans cells in histiocytosis X?

Accepted Answer

Abundant Birbeck granules

Answer

Eosinophilic cytoplasm

Answer

Bean-shaped nucleus

Answer

Large nucleoli

Question 11

Which virus is commonly associated with infectious mononucleosis?

Accepted Answer

Epstein-Barr virus

Answer

Cytomegalovirus

Answer

Herpes simplex virus

Answer

Varicella-zoster virus

Question 12

In developed countries, what is the most common cause of secondary lymphedema?

Accepted Answer

Cancer

Answer

Infection

Answer

Trauma

Answer

Obesity

Question 13

What is the characteristic histologic feature of Hodgkin lymphoma?

Accepted Answer

Reed-Sternberg cells

Answer

Large, atypical lymphocytes

Answer

Small, mature lymphocytes

Answer

Hispanocytes

Question 14

What is the recommended primary treatment for localized, early-stage non-Hodgkin lymphoma?

Accepted Answer

Radiation therapy

Answer

Chemotherapy

Answer

Immunotherapy

Answer

Stem cell transplant

Question 15

Which of the following is a major function of the thymus gland?

Accepted Answer

Maturation of T lymphocytes

Answer

Production of B lymphocytes

Answer

Storage of mature lymphocytes

Answer

Synthesis of antibodies

Question 16

What is the most common site of metastasis for breast cancer?

Accepted Answer

Bone

Answer

Lung

Answer

Liver

Answer

Brain

Question 17

Which of the following is NOT a characteristic of multiple myeloma?

Accepted Answer

Neutropenia

Answer

Presence of monoclonal plasma cells

Answer

Lytic bone lesions

Answer

Hypercalcemia

Question 18

What type of immune response is primarily mediated by antibodies?

Accepted Answer

Humoral immunity

Answer

Cell-mediated immunity

Answer

Innate immunity

Answer

Adaptive immunity

Question 19

What is the recommended initial diagnostic test used to screen for HIV infection?

Accepted Answer

ELISA

Answer

Western blot

Answer

Viral load assay

Answer

CD4 count

Question 20

Which of the following is the least common cause of lymphedema?

Accepted Answer

Cardiac insufficiency

Answer

Trauma

Answer

Infection

Answer

Neoplasia

Question 21

Which of the following is a primary function of the thymus gland?

Accepted Answer

Maturation of T cells

Answer

Production of antibodies

Answer

Storage of immune cells

Answer

Filtration of blood

Question 22

Which type of immune response is involved in allergies?

Accepted Answer

Type I

Answer

Type II

Answer

Type III

Answer

Type IV

Question 23

Which cell type presents antigens to CD8+ T cells?

Accepted Answer

Dendritic cell

Answer

B cell

Answer

T cell

Answer

Macrophage

Question 24

Which genetic translocation is commonly observed in multiple myeloma?

Accepted Answer

t(11;14)

Answer

t(15;17)

Answer

t(9;22)

Question 25

How do immunohistochemistry and flow cytometry work together to diagnose and classify acute leukemia?

Accepted Answer

Immunohistochemistry and flow cytometry enhance each other's accuracy in diagnosing acute leukemia.

Answer

Immunohistochemistry is not helpful in diagnosing acute leukemia.

Answer

Flow cytometry alone can provide a definitive diagnosis of acute leukemia.

Answer

Flow cytometry is mainly used to predict the outcome of acute leukemia.

Question 26

Which characteristic feature is uniquely associated with Hodgkin lymphoma?

Accepted Answer

Presence of Reed-Sternberg cells

Answer

Absence of neoplastic lymphocytes

Answer

High incidence in children

Answer

Non-clonal origin

Question 27

**Which of the following is a common characteristic of lymphatic and immune system diseases:**

Accepted Answer

Chronic inflammation

Answer

Absence of abnormal cell growth

Answer

Absence of fever

Question 28

Which clinical manifestation is commonly associated with lymphatic and immune system diseases?

Accepted Answer

Swollen and enlarged lymph nodes

Answer

Reduced white blood cell production

Answer

Absence of fever

Answer

Increased appetite

Question 29

Which of the following is a common clinical presentation of acute myeloid leukemia?

Accepted Answer

Anemia, thrombocytopenia, and neutropenia

Answer

Enlarged lymph nodes

Answer

Skin rash

Answer

Weight loss

Question 30

Which cell type is primarily affected in chronic lymphocytic leukemia?

Accepted Answer

B lymphocytes

Answer

Neutrophils

Answer

Erythrocytes

Answer

T lymphocytes

Question 31

Which immunoglobulin is often elevated in multiple myeloma?

Accepted Answer

IgG

Answer

IgM

Answer

IgA

Answer

IgE

Question 32

Which of the following is a common cytogenetic abnormality in chronic myeloid leukemia?

Accepted Answer

Philadelphia chromosome

Answer

Trisomy 8

Answer

Deletion 6q

Answer

Inversion 16

Question 33

Which of the following is a key diagnostic test for lymphoproliferative disorders?

Accepted Answer

Flow cytometry

Answer

Urinalysis

Answer

Chest X-ray

Answer

Electrocardiogram

Question 34

Which of the following is a distinctive hallmark of Hodgkin lymphoma?

Accepted Answer

Presence of Reed-Sternberg cells

Answer

Predominance of centrocytes

Answer

Presence of Burkitt cells

Answer

Abundance of immunoblasts

Question 35

Immunodeficiency, a weakened immune system, is commonly associated with which of the following diseases?

Accepted Answer

HIV/AIDS

Answer

Rheumatoid arthritis (an autoimmune disorder)

Answer

Multiple sclerosis (a demyelinating disorder)

Question 36

Which type of hypersensitivity reaction is primarily mediated by IgE antibodies, triggering immediate allergic responses?

Accepted Answer

Type I

Answer

Type II (antibody-mediated)

Answer

Type IV (cell-mediated)

Answer

Type III (immune complex-mediated)

Question 37

The thymus, a specialized organ, plays a crucial role in the development and maturation of which immune cells?

Accepted Answer

T lymphocytes

Answer

Macrophages

Answer

Natural killer cells

Answer

B lymphocytes

Question 38

Which type of immune response involves the production and secretion of antibodies, providing protection against pathogens?

Accepted Answer

Humoral immunity

Answer

Innate immunity (non-specific defenses)

Answer

Adaptive immunity (a broader category encompassing both humoral and cell-mediated responses)

Answer

Cell-mediated immunity (involving direct action of immune cells)

Question 39

Systemic lupus erythematosus (SLE), an autoimmune disorder, is characterized by the presence of which type of autoantibodies?

Accepted Answer

Autoantibodies against nuclear antigens

Answer

Anti-smooth muscle antibodies

Answer

Anti-neutrophil cytoplasmic antibodies

Answer

Anti-mitochondrial antibodies

Question 40

In non-Hodgkin lymphoma, a type of cancer affecting the lymphatic system, which anatomical site is most commonly involved?

Accepted Answer

Lymph nodes

Answer

Spleen

Answer

Bone marrow

Answer

Thyroid

Question 41

Which of the following factors is a major risk factor for the development of lymphatic filariasis, a parasitic infection affecting the lymphatic system?

Accepted Answer

Living in areas where the disease is endemic

Answer

Gender

Answer

Age

Answer

Occupation

Question 42

Acute appendicitis, an inflammatory condition of the appendix, is histologically characterized by:

Accepted Answer

Neutrophilic infiltration and inflammation

Answer

Granulomatous inflammation (characteristic of certain infections)

Answer

Eosinophilic infiltration (more common in parasitic infections)

Answer

Lymphocytic infiltration (seen in chronic inflammation)

Question 43

Which of the following accurately describes the primary function of the lymphatic system?

Accepted Answer

Drains excess fluid and waste products from tissues back into the bloodstream

Answer

Transports hormones

Answer

Produces blood cells

Question 44

Which type of cell predominates within lymph nodes, playing a crucial role in the immune response?

Accepted Answer

Lymphocyte

Answer

Macrophage

Answer

Fibroblast

Answer

Neutrophil

Question 45

Select the most common symptom associated with lymphedema:

Accepted Answer

Swelling in the affected area

Answer

Shortness of breath

Answer

Fever

Answer

Nausea

Question 46

In humoral immunity, which antibody class plays a predominant role?

Accepted Answer

Immunoglobulin G (IgG)

Answer

Immunoglobulin E (IgE)

Answer

Immunoglobulin A (IgA)

Answer

Immunoglobulin M (IgM)

Question 47

Which type of immune cell is specifically responsible for engulfing and destroying foreign particles and cellular debris?

Accepted Answer

Macrophage

Answer

Eosinophil

Answer

Lymphocyte

Answer

Neutrophil

Question 48

Rheumatoid arthritis is commonly treated with which type of medication?

Accepted Answer

Disease-modifying antirheumatic drugs (DMARDs)

Answer

Antibiotics

Answer

Chemotherapy

Answer

Radiation therapy

Question 49

Which type of primary immunodeficiency disease has the highest prevalence?

Accepted Answer

Common variable immunodeficiency (CVID)

Answer

Severe combined immunodeficiency (SCID)

Answer

X-linked agammaglobulinemia

Answer

DiGeorge syndrome

Question 50

The thymus plays a crucial role in the immune system by serving as the site for:

Accepted Answer

Maturation and selection of T cells

Answer

Production of antibodies

Answer

Filtration of blood

Answer

Storage of immune cells