Major Neurotransmitter Systems: Interactive Learning Quizzes

Question 1

Which neurotransmitter triggers the physiological response known as the 'fight-or-flight' reaction?

Accepted Answer

Epinephrine

Answer

Dopamine

Answer

Serotonin

Question 2

Which of the following is NOT a major neurotransmitter system covered in this unit?

Accepted Answer

GABAergic

Answer

Dopaminergic

Answer

Cholinergic

Answer

Serotonergic

Question 3

Acetylcholine, a neurotransmitter in the cholinergic system, is primarily responsible for:

Accepted Answer

Muscle contraction and autonomic functions

Answer

Sensory perception

Answer

Mood regulation

Answer

Memory consolidation

Question 4

Which of the following is the primary site of action for norepinephrine in the adrenergic system?

Accepted Answer

Postsynaptic alpha-1 receptors

Answer

Sympathetic ganglia

Answer

Postsynaptic beta-2 receptors

Answer

Presynaptic autoreceptors

Question 5

The serotonin transporter (SERT) is responsible for:

Accepted Answer

Reuptaking serotonin from the synaptic cleft

Answer

Degrading serotonin in the presynaptic terminal

Answer

Synthesizing serotonin in the presynaptic neuron

Answer

Releasing serotonin from the presynaptic neuron

Question 6

Which of the following drugs acts as a selective serotonin reuptake inhibitor (SSRI)?

Accepted Answer

Fluoxetine

Answer

Propranolol

Answer

Clonidine

Answer

Phenylephrine

Question 7

Which of the following neurotransmitter systems is implicated in Parkinson's disease?

Accepted Answer

Dopaminergic

Answer

Serotonergic

Answer

Cholinergic

Answer

GABAergic

Question 8

Which of the following techniques is commonly used to study neurotransmitter systems in the living brain?

Accepted Answer

Positron emission tomography (PET)

Answer

Electroencephalography (EEG)

Answer

Magnetic resonance imaging (MRI)

Answer

Immunohistochemistry

Question 9

In the cholinergic system, which enzymatic step is catalyzed by choline acetyltransferase?

Accepted Answer

Acetylcholine synthesis

Answer

Acetylcholine hydrolysis

Answer

Choline uptake

Answer

Acetyl-CoA synthesis

Question 10

Which brain region exhibits impaired neurotransmission in Parkinson's disease?

Accepted Answer

Basal ganglia

Answer

Cerebellum

Answer

Hippocampus

Question 11

Which of the following medications has cholinergic agonist properties?

Accepted Answer

Nicotine

Answer

Atropine

Answer

Propranolol

Answer

Fluoxetine

Question 12

Which type of receptor is primarily targeted by selective serotonin reuptake inhibitors (SSRIs)?

Accepted Answer

Serotonin 5-HT1A

Answer

Serotonin 5-HT2A

Answer

Dopamine D2

Answer

Norepinephrine alpha-1

Question 13

Which neurotransmitter system is predominantly involved in the fight-or-flight response?

Accepted Answer

Adrenergic

Answer

Cholinergic

Answer

Serotonergic

Answer

GABAergic

Question 14

Where is the primary site of action for acetylcholinesterase inhibitors?

Accepted Answer

Acetylcholinesterase enzyme

Answer

Cholinergic receptors

Answer

Dopamine transporters

Answer

Serotonin reuptake pumps

Question 15

Which of the following is a potential adverse effect of adrenergic alpha-1 receptor blockers?

Accepted Answer

Hypotension

Answer

Tachycardia

Answer

Bronchospasm

Answer

Hyperglycemia

Question 16

Which neurotransmitter is primarily responsible for inhibitory postsynaptic potentials (IPSPs) in the central nervous system?

Accepted Answer

GABA

Answer

Glutamate

Answer

Dopamine

Answer

Serotonin

Question 17

Which brain region contains a significant number of serotonergic neurons?

Accepted Answer

Medial forebrain bundle

Answer

Basal ganglia

Answer

Cerebellum

Answer

Hypothalamus

Question 18

Acetylcholine is a neurotransmitter synthesized from:

Accepted Answer

Choline and acetyl-CoA

Answer

Tyrosine and dopamine

Answer

Tryptophan and 5-hydroxytryptamine

Answer

Glutamic acid and GABA

Question 19

Which of the following drugs blocks cholinergic neurotransmission?

Accepted Answer

Atropine

Answer

Acetylcholine

Answer

Dopamine

Answer

Serotonin

Question 20

Epinephrine and norepinephrine are neurotransmitters belonging to which system?

Accepted Answer

Adrenergic system

Answer

Cholinergic system

Answer

Serotonergic system

Answer

GABAergic system

Question 21

Which drug is an example of a selective serotonin reuptake inhibitor (SSRI)?

Accepted Answer

Fluoxetine

Answer

Propranolol

Answer

Naloxone

Answer

Diazepam

Question 22

Parkinson's disease is associated with a deficiency of:

Accepted Answer

Dopamine

Answer

Serotonin

Answer

Noradrenaline

Answer

Acetylcholine

Question 23

Which technique is used to directly measure neurotransmitter levels in the brain?

Accepted Answer

Microdialysis

Answer

Electroencephalography

Answer

Magnetic resonance imaging

Answer

Positron emission tomography

Question 24

Which neurotransmitter is primarily associated with memory and attention?

Accepted Answer

Acetylcholine

Answer

Dopamine

Answer

Serotonin

Answer

Norepinephrine

Question 25

Which drug belongs to the class of selective serotonin reuptake inhibitors (SSRIs) and is commonly used in treating depression?

Accepted Answer

Fluoxetine

Answer

Amitriptyline

Answer

Clonidine

Answer

Haloperidol

Question 26

Which neurotransmitter system is primarily responsible for mediating the physiological response known as the "fight-or-flight" response?

Accepted Answer

Sympathetic nervous system

Answer

Parasympathetic nervous system

Answer

Enteric nervous system

Answer

Central nervous system

Question 27

Which neurodegenerative disorder is characterized by a significant loss of cholinergic neurons in the basal forebrain?

Accepted Answer

Alzheimer's disease

Answer

Parkinson's disease

Answer

Huntington's disease

Answer

Multiple sclerosis

Question 28

Which receptor subtype is involved in regulating heart rate and blood pressure?

Accepted Answer

β1-adrenergic

Answer

M1-muscarinic

Answer

M2-muscarinic

Answer

α1-adrenergic

Question 29

Which neurotransmitter system is primarily responsible for producing melatonin?

Accepted Answer

Serotonergic system

Answer

Cholinergic system

Answer

Dopaminergic system

Answer

GABAergic system

Question 30

Which muscarinic receptor subtype mediates the inhibitory effects of acetylcholine on the heart?

Accepted Answer

M2-muscarinic

Answer

M1-muscarinic

Answer

α1-adrenergic

Answer

β2-adrenergic

Question 31

The primary neurotransmitter in the parasympathetic nervous system is:

Accepted Answer

Acetylcholine

Answer

Dopamine

Answer

Epinephrine

Answer

Serotonin

Question 32

Which receptor subtype mediates the vasoconstrictor effects of epinephrine?

Accepted Answer

α1-adrenoreceptor

Answer

α2-adrenoreceptor

Answer

β1-adrenoreceptor

Answer

β2-adrenoreceptor

Question 33

The primary site of action of selective serotonin reuptake inhibitors (SSRIs) is:

Accepted Answer

Serotonin transporters

Answer

Dopamine transporters

Answer

Norepinephrine transporters

Answer

GABA transporters

Question 34

Which neurotransmitter is implicated in reward and addiction?

Accepted Answer

Dopamine

Answer

Acetylcholine

Answer

GABA

Answer

Serotonin

Question 35

Atropine is an antagonist at which type of acetylcholine receptor?

Accepted Answer

Muscarinic

Answer

Nicotinic

Answer

Ionotropic

Answer

Metabotropic

Question 36

The neurotransmitter released at the neuromuscular junction is:

Accepted Answer

Acetylcholine

Answer

Glycine

Answer

Glutamate

Answer

Dopamine

Question 37

The enzyme responsible for synthesizing acetylcholine is:

Accepted Answer

Choline acetyltransferase

Answer

Tyrosine hydroxylase

Answer

Tryptophan hydroxylase

Answer

Dopamine β-hydroxylase

Question 38

Which neurotransmitter mediates inhibitory neurotransmission in the central nervous system?

Accepted Answer

GABA

Answer

Glycine

Answer

Glutamate

Answer

Aspartate

Question 39

The primary action of monoamine oxidase inhibitors (MAOIs) is to:

Accepted Answer

Inhibit monoamine oxidase

Answer

Stimulate monoamine release

Answer

Block monoamine reuptake

Answer

Enhance monoamine synthesis

Question 40

Which neurotransmitter is primarily involved in memory consolidation and synaptic plasticity in the brain?

Accepted Answer

Glutamate

Answer

Serotonin

Answer

Dopamine

Question 41

Which receptor subtype is primarily targeted by nicotine in the central nervous system?

Accepted Answer

Nicotinic acetylcholine receptor

Answer

GABA receptor

Answer

Muscarinic acetylcholine receptor

Answer

Glutamate receptor

Question 42

Which neurotransmitter is a major neurotransmitter involved in the body's stress response and sympathetic nervous system activation?

Accepted Answer

Epinephrine

Answer

GABA

Answer

Serotonin

Answer

Acetylcholine

Question 43

Which drug class selectively targets and inhibits the reuptake of serotonin in the synaptic cleft, enhancing its availability?

Accepted Answer

Fluoxetine (Prozac)

Answer

Valproic acid (Depakote)

Answer

Lamotrigine (Lamictal)

Answer

Lithium

Question 44

Which neurotransmitter is primarily involved in the regulation of sleep-wake cycles, promoting inhibitory effects in the brain?

Accepted Answer

GABA

Answer

Dopamine

Answer

Glutamate

Answer

Norepinephrine

Question 45

Which receptor subtype mediates the inhibitory effects of GABA in the central nervous system, leading to hyperpolarization?

Accepted Answer

GABA-A receptor

Answer

Glycine receptor

Answer

GABA-B receptor

Answer

NMDA receptor

Question 46

Which neurotransmitter is primarily involved in reward pathways and motivation in the brain?

Accepted Answer

Dopamine

Answer

Serotonin

Answer

Norepinephrine

Answer

Acetylcholine

Question 47

Which neurotransmitter is predominantly involved in the parasympathetic nervous system, playing a crucial role in rest-and-digest functions?

Accepted Answer

Acetylcholine

Answer

Serotonin

Answer

Norepinephrine

Answer

Epinephrine

Question 48

Long-term use of amphetamines, a class of drugs, is known to have detrimental effects on which neurotransmitter system?

Accepted Answer

Dopamine

Answer

GABA

Answer

Acetylcholine

Answer

Serotonin

Question 49

Which neurotransmitter is the main excitatory neurotransmitter in the central nervous system?

Accepted Answer

Glutamate

Answer

Dopamine

Answer

Serotonin

Answer

GABA

Question 50

Which neurotransmitter system is associated with the regulation of mood, sleep, and anxiety?

Accepted Answer

Serotonergic system

Answer

Cholinergic system

Answer

Adrenergic system

Answer

Dopaminergic system

Question 51

Which neurotransmitter is released at the neuromuscular junction, facilitating muscle contraction?

Accepted Answer

Acetylcholine

Answer

Serotonin

Answer

Norepinephrine

Answer

Dopamine

Question 52

Which second messenger is primarily associated with the adrenergic system's signaling pathways?

Accepted Answer

cAMP

Answer

IP3

Answer

DAG

Answer

Ca2+

Question 53

Which neurotransmitter plays a crucial role in the reward pathway of the brain?

Accepted Answer

Dopamine

Answer

Serotonin

Answer

Acetylcholine

Answer

Glutamate

Question 54

Which of the following is an example of a tricyclic antidepressant?

Accepted Answer

Amitriptyline

Answer

Venlafaxine

Answer

Fluoxetine

Answer

Sertraline

Question 55

Which neurotransmitter system is primarily responsible for regulating blood pressure through its sympathetic division?

Accepted Answer

Sympathetic nervous system

Answer

Enteric nervous system

Answer

Parasympathetic nervous system

Answer

Somatic nervous system

Question 56

Which type of antidepressant is Fluoxetine classified as?

Accepted Answer

Selective serotonin reuptake inhibitor (SSRI)

Answer

Serotonin and norepinephrine reuptake inhibitor

Answer

Monoamine oxidase inhibitor

Answer

Tricyclic antidepressant

Question 57

Which neurotransmitter is primarily responsible for inhibiting movement?

Accepted Answer

GABA

Answer

Serotonin

Answer

Glutamate

Answer

Dopamine