Bioactive Composite Scaffolds for Tissue Regeneration and Repair

Question 1

Which of the following is a primary advantage of bioactive composite scaffolds in tissue engineering?

Accepted Answer

Enhanced cell adhesion and proliferation

Answer

Reduced risk of infection

Answer

Superior mechanical strength

Answer

Lower production costs

Question 2

When selecting a bioactive molecule for incorporation into a composite scaffold, which factor is most important to consider?

Accepted Answer

Biological activity

Answer

Biodegradability

Answer

Solubility

Answer

Toxicity

Question 3

What is the significance of osteoinductivity in bioactive composite scaffolds for bone regeneration?

Accepted Answer

It promotes bone formation by stimulating stem cells

Answer

It enhances vascularization of the scaffold

Answer

It prevents immune rejection

Answer

It improves mechanical strength

Question 4

Which of the following characteristics is crucial for a bioactive composite scaffold intended for use in soft tissue repair?

Accepted Answer

Low elastic modulus

Answer

High porosity

Answer

Antimicrobial properties

Answer

Electrical conductivity

Question 5

What is a fundamental advantage associated with incorporating bioactive cues into composite scaffolds?

Accepted Answer

Enhanced cell adhesion and proliferation

Answer

Improved mechanical stability

Answer

Reduced immune response

Answer

Lowered production costs

Question 6

How does the incorporation of hydroxyapatite into a composite scaffold impact its mechanical properties?

Accepted Answer

Increases stiffness and strength

Answer

Decreases stiffness and strength

Answer

Improves biodegradability

Answer

Has no significant effect

Question 7

What is a potential advantage of incorporating natural polymers in composite scaffold design?

Accepted Answer

Biodegradability and biocompatibility

Answer

High mechanical strength

Answer

Low cost

Answer

Ease of synthesis

Question 8

Which of the following biomaterials is commonly used to create bioactive composite scaffolds for bone tissue engineering?

Accepted Answer

Hydroxyapatite

Answer

Polyethylene

Answer

Gold

Answer

Titanium

Question 9

What is a key advantage of using composite scaffolds over single-material scaffolds in tissue engineering?

Accepted Answer

Enhanced mechanical strength and biocompatibility

Answer

Increased cell adhesion and proliferation

Answer

Improved nutrient delivery

Answer

Reduced risk of infection

Question 10

What is the primary role of growth factors incorporated into bioactive composite scaffolds?

Accepted Answer

To attract and stimulate cell growth and differentiation

Answer

To strengthen the mechanical properties of the scaffold

Answer

To prevent infection

Answer

To improve the scaffold's biodegradability

Question 11

What is a key advantage of using a biodegradable scaffold over a non-biodegradable scaffold in tissue engineering?

Accepted Answer

Elimination of the need for surgical removal after tissue regeneration

Answer

Reduced risk of infection

Answer

Improved cell adhesion

Answer

Enhanced mechanical strength

Question 12

Identify a key characteristic of bioactive composite scaffolds:

Accepted Answer

They stimulate cell adhesion and proliferation

Answer

They exhibit low mechanical durability

Answer

They have high electrical resistivity

Answer

They degrade rapidly

Question 13

Which material is commonly used in the fabrication of bioactive composite scaffolds?

Accepted Answer

Hydroxyapatite

Answer

Polyethylene terephthalate

Answer

Titanium alloy

Answer

Polystyrene

Question 14

Which fabrication technique is suitable for creating bioactive composite scaffolds with interconnected porosity?

Accepted Answer

3D printing

Answer

Injection molding

Answer

Cold pressing

Answer

Centrifugation

Question 15

What is the main function of bioactive ions in bioactive composite scaffolds?

Accepted Answer

To enhance cellular interactions

Answer

To increase mechanical stability

Answer

To prevent scaffold degradation

Answer

To conduct electrical signals

Question 16

Identify a significant challenge associated with the clinical application of bioactive composite scaffolds:

Accepted Answer

Immune response

Answer

Limited scaffold lifespan

Answer

Complex sterilization procedures

Answer

High material cost

Question 17

Which research direction holds promise in the development of bioactive composite scaffolds?

Accepted Answer

Incorporating growth factors

Answer

Reducing scaffold porosity

Answer

Increasing scaffold rigidity

Answer

Eliminating synthetic materials

Question 18

Which type of cell is most commonly incorporated into bioactive composite scaffolds for tissue regeneration applications?

Accepted Answer

Stem cells

Answer

Macrophages

Answer

Fibroblasts

Answer

Neurons

Question 19

To promote angiogenesis within a tissue scaffold, which of the following design features is crucial?

Accepted Answer

High porosity

Answer

Low stiffness

Answer

Non-fouling surface

Answer

Rapid biodegradation

Question 20

In the context of cartilage regeneration, which natural polymer is commonly employed as a component of bioactive composite scaffolds?

Accepted Answer

Chitosan

Answer

Polyetheretherketone

Answer

Polycaprolactone

Answer

Poly(lactic acid)

Question 21

A scaffold capable of releasing bioactive molecules in a controlled manner over time is known as:

Accepted Answer

Drug-eluting scaffold

Answer

Self-healing scaffold

Answer

Conductive scaffold

Answer

Porous scaffold

Question 22

Which technique is commonly employed to evaluate the mechanical properties, such as tensile strength and modulus, of bioactive composite scaffolds?

Accepted Answer

Tensile testing

Answer

Atomic force microscopy

Answer

X-ray diffraction

Answer

Gas chromatography

Question 23

In the United States, which regulatory agency is responsible for evaluating and approving bioactive composite scaffolds for clinical applications?

Accepted Answer

Food and Drug Administration (FDA)

Answer

National Institutes of Health (NIH)

Answer

Environmental Protection Agency (EPA)

Answer

Occupational Safety and Health Administration (OSHA)